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• ↓ The Max Perutz Labs are dedicated to a mechanistic understanding of fundamental biomedical processes. By analyzing and reconstituting complex biological systems across different scales, our scientists aim to link breakthroughs in basic research to advances in human health.
• ↓ Scientific Facilities
• ↓ From Mechanism to Medicine
• ↓ “In science, truth always wins.”
• ↓ A workplace that values diversity and internationality
• ↓ Inspiring and enabling the next generation
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"Perutz group leader Bojan Žagrović is part of the newly funded Marie Skłodowska-Curie (MSCA) Doctoral Network ‘PhaseCat’, which brings together five academic research groups and two companies across Europe to investigate the catalytic potential of protein-RNA condensates. Coordinated by Wim De Malsche at Vrije Universiteit Brussel in Belgium, the four-year network has a total funding volume of €2.6 million and will support nine PhD researchers, two of them associated with the Žagrović group including one jointly mentored with a group at Vrije Universiteit Brussel."

"Building an autophagosome requires cells to rapidly assemble and expand membranes at the right place and time. In a new study published in Nature Communications, first author Elisabeth Holzer from the Martens lab found that the lipid composition of mammalian precursor membranes differ substantially from their yeast counterparts. The team identified the lipid transport protein ATG2A and ATG8-like proteins on the nascent phagophore membrane as key factors in delivering the phosphatidylinositol (PI) required to drive membrane biogenesis. By clarifying how autophagosome formation is controlled, the findings may help better understand how defects in autophagy contribute to neurodegenerative diseases such as Parkinson’s."

"In their ‘Researcher of the Month’ series, the Medical University of Vienna features outstanding scientists and their work. In September, group leader Marco Hein was selected for his postdoctoral work at the Chan Zuckerberg Biohub in San Francisco, where he developed a high-throughput method to map protein localization across cellular compartments, providing new insights into how cells organize and regulate their proteins in space and time."

"Genome engineering is constantly searching for new and promising molecular tools – and CRISPR-associated transposons (CASTs) are among them. A new study in Nature Communications from the Querques lab, with Mateusz Walter as a co-first author, reveals how CASTs precisely control DNA transposition. Combining cryo-EM with biochemistry, the researchers uncovered a series of molecular checkpoints that determine how and when the CAST transposase acts."

Key Topics & Focus Areas for maxperutzlabs.ac.at:

The Max Perutz Labs are dedicated to a mechanistic understanding of fundamental biomedical processes. By analyzing and reconstituting complex biological systems across different scales, our scientists aim to link breakthroughs in basic research to advances in human health.

Scientific Facilities

From Mechanism to Medicine

“In science, truth always wins.”

A workplace that values diversity and internationality

Inspiring and enabling the next generation